Well, the train is probably the easiest mode of transportation. You don’t have to worry about the rising cost of gas (or running out of it,) who will drive, how tired you will be if you drive, weather conditions (most of the time,) or arriving 31 hours early for your flight. If you want a scenic trip, take the train! You’ll get to relax, spread out a little more than you would in a car or on a cramped flight, and watch the changing leaves or budding trees, while also being able to get up to walk around and stretch a bit.
My only suggestion for booking a train (for longer destinations) would be to do it one week (or more) in advance. If you wait until the last minute, like anything really, you’ll run the risk of not finding a train, or having your tickets be incredibly expensive.
Check out the tons of destinations Amtrak has to offer. Their website is extremely easy to use, and they also accept tons of discounts for AAA, senior citizen, children, student advantage, and many other options. If you plan on traveling a lot by train, or commute from school or your home to an internship, for example, I would highly recommend signing up for the student advantage card. That way, you always receive a 15% off discount, as well as many other perks, like receiving up to 50% off while you’re shopping for clothes or food!